- Directors: Rob Marshall
- Producers: Bob Weinstein, Harvey Weinstein, Craig Zadan, Martin Richards
- Writers: Maurine Watkins, Bob Fosse, Fred Ebb, Bill Condon
- Genres: Crime, Drama, Musical
- Actors: Catherine Zeta Jones, Richard Gere, Queen Latifah, John C Reilly, Taye Diggs, Christine Baranski
The film takes place in Chicago, circa 1924. Naive Roxie Hart (RenÃ©e Zellweger) visits a nightclub where star Velma Kelly (Catherine Zeta-Jones) performs (“And All That Jazz”). Hart is having an affair with Fred Casely (Dominic West) in hopes that he will get her a gig as a vaudeville star. Velma is arrested after the show for murdering her adulterous husband and sister Veronica after finding them in bed together. After Roxie realizes that Fred will not help her break into show business, she kills him in a fit of rage and tries to make her simple-minded husband Amos (John C. Reilly) take the fall (“Funny Honey”). However, the police and Amos (realizing she has been unfaithful to him) see through her ruse and Roxie is arrested and sent to the Cook County Jail.
Once Roxie arrives and is booked, she is sent to Murderess’ Row to await trial, under the care of the corrupt Matron “Mama” Morton (Queen Latifah), who supplies her girls with cigarettes and other materials if she is paid well enough (“When You’re Good to Mama”). Roxie meets Velma in jail as the woman in charge, and learns the stories behind the other women in Murderess’ Row (“Cell Block Tango”). Roxie decides that she wants Velma’s lawyer Billy Flynn (Richard Gere) to get her off (“All I Care About”), and convinces her husband to talk to him. Billy decides to take Roxie’s case and get her off by making her a star.
With nothing left, Roxie once more sets off to find a stage career, with little success (“Nowadays”). However, she is soon approached by Velma, who is willing to revive a two-person act with Roxie. Roxie refuses at first, because of the hatred that they share for each other, but relents. The two murderesses, no longer facing jail time, finally become the enormous successes they have been longing to be (“Nowadays”/”Hot Honey Rag”).