- Directors: Sergio Leone
- Producers: Arrigo Colombo, Giorgio Papi
- Writers: Sergio Leone, A Bonzzoni, Jaime Comas Gil
- Genres: Action, Western
- Actors: Clint Eastwood, Marianne Koch, Joseph Egger, Antonio Prieto, Mario Brega, Wolfgang Lukschy, Sieghardt Rupp, Benny Reeves
A Man with No Name (Clint Eastwood), arrives at a little Mexican border town named San Miguel. He is quickly introduced to the feud between two families vying to gain control the town: the Rojo brothers, consisting of Don Miguel (the eldest and nominally in charge), Esteban (Sieghardt Rupp) (the most headstrong) and RamÃ³n (the most capable and intelligent, played by Gian Maria VolontÃ¨, who would reappear in For a Few Dollars More as the psychopathic El Indio), and the family of so-called “town sheriff” John Baxter (Wolfgang Lukschy).
The Stranger quickly spies an opportunity to make a “fistful of dollars” and decides to play both families against each other. His opportunity comes when a detachment of Mexican soldiers escorting a shipment of gold passes through the town. The gold is ostensibly being delivered to a troop of American soldiers at the border river in exchange for a shipment of modern American weapons, but upon following the Mexican troops, the Stranger watches from hiding as they are massacred by members of the Rojo gang, disguised in American uniforms and led by Ramon Rojo.
The Stranger takes two of the bodies to a nearby cemetery and sells information to both sides that two soldiers survived the attack. Both sides race to the cemetery, the Baxters to get the “survivors” to testify against the Rojos, and the Rojos to silence them. The factions engage in a fierce gunfight, but Ramon manages to kill (as he believes) the “survivors” and Esteban captures John Baxter’s son Antonio. While the Rojos and the Baxters are busy, the Stranger takes the opportunity to search the Rojo hacienda, but accidentally knocks out RamÃ³n’s prisoner and unwilling mistress Marisol (Marianne Koch) when she surprises him. He takes her to the Baxters, who arrange for a prisoner swap with the Rojos.
The Man with No Name returns to town to engage the Rojos in a dramatic duel. He first rescues Silvanito, who was tortured to reveal the Stranger’s whereabouts. The Man with No Name kills Ramon and the remaining Rojos, except Esteban (who is shot by Silvanito), and rides away.