- Directors: John Putch
- Producers: Mike Elliot
- Writers: David H Steinberg
- Genres: Comedy
- Actors: Louisa Lytton, John Patrick Jordan, Kevin M Horton, Brandon Hardesty, Eugene Levy, Nico McEown, Adrienne Carter, Bug Hall
The story takes place at East Great Falls High, ten years after the First American Pie movie. The new protagonists of this movie are three brand new hapless virgins: Rob (Bug Hall), Nathan (Kevin M. Horton) and Lube (Brandon Hardesty). One night Rob accidentally set’s fire to the school library, and finds the Bible, Mr. Levenstein’s (Eugene Levy) creation. Unfortunately for them, the book is ruined. The book had incomplete advice, and embarks them on a helpless but hilarious journey to lose their virginity. After trying and failing for most of time, they pledge to restore the book, and to do this, they must find the original author of the book (Levenstein) and all the other people who wrote on the book, and start the restoration.